Pathogen host co-evolution

Pathogens enjoy the benefit of rapid generation times and enormous population sizes, yet hosts don’t typically die of infection in nature. How do they manage to resist attack despite the potential for ever-escalating arms races? We have found that A. thaliana harbors many ancient balanced polymorphisms at R-genes involved in the recognition of pathogens, and that these polymorphisms are maintained long-term amidst complex ecological interactions. Our current focus is on how the (co)evolution of generalists differs from specialists, and how we can understand pathogen host interactions in the face of community complexity.

New Projects

> Local adaptation and the accessory genome in Pseudomonas syringae

Previous Projects

> The evolution of resistance to pathogens

> Evolution of pathogenicity and intraspecific interactions in Pseudomonas syringae

> PAMP induced growth responses in Arabidopsis thaliana

> Genetic basis of a natural plant pathosystem

University of Chicago, Dept. of Ecology & Evolution